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Filtered Search Results
eMolecules 887245-74-1 | 3-Aminoquinoline-2-carboxylic acid | MFCD13189674 | 250mg
Ambeed | 3-Aminoquinoline-2-carboxylic acid | 250mg | 595927622 | A840863 | 887245-74-1 | MFCD13189674 | 188.186 | C10H8N2O2
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Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 250 MG
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Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker used in the synthesis of PROTACs. PROTACs, or Proteolysis-targeting chimeras, consist of two different ligands connected by a linker. One ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based (8 units) linker
- Can be used in the synthesis of PROTACs
- Ligands connected by a linker target E3 ubiquitin ligase and protein of interest
- Utilizes intracellular ubiquitin-proteasome system to selectively degrade target proteins
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eMolecules 2246-44-8 | 2-Methylnaphthalen-1-amine | Ambeed | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 5g | 528570193
2-Methylnaphthalen-1-amine | Ambeed | 2246-44-8 | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 5g | 528570193
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eMolecules 496806-75-8 | 2-Aminoquinoline-5-carboxylic acid | Oakwood Chemicals | MFCD01836227 | 188.186 | C10H8N2O2 | 98.000 | Nc1ccc2c(cccc2n1)C(O)=O | 1g | 480159209
2-Aminoquinoline-5-carboxylic acid | Oakwood Chemicals | 496806-75-8 | MFCD01836227 | 188.186 | C10H8N2O2 | 98.000 | Nc1ccc2c(cccc2n1)C(O)=O | 1g | 480159209
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Medchemexpress LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341, MFCD26793840 | 99.7% | 432.39 | C22H27Cl2N5 | 50 MG
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TLR7/8 agonist 1 dihydrochloride is an imidazoquinoline-based small molecule that functions as a dual agonist of Toll-like receptors 7 and 8. Supplied as a dihydrochloride salt in solid form, it is intended for research use in immunostimulation and TLR signaling studies and includes recommended solubility and storage guidance.
- Dual TLR7/TLR8 agonist activity suitable for immunostimulation studies.
- Dihydrochloride salt form improves solubility and handling.
- High purity (99.7%) for reproducible experimental results.
- Solid, off-white to light yellow appearance for easy visual inspection.
- Highly soluble in DMSO; in vitro and in vivo formulation protocols provided.
- Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Mal-C6-amine TFA | 731862-92-3 | MFCD11519191 | 99.7% | 310.27 g/mol | C12H17F3N2O4 | 250 MG
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Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker supplied as the trifluoroacetate salt for use in the synthesis of proteolysis-targeting chimeras. It provides a maleimide-reactive terminus and a six-carbon spacer that enable thiol conjugation and optimized linker length for degrader constructs.
- Maleimide-reactive terminus for selective conjugation to thiols.
- C6 alkyl spacer provides flexibility and appropriate linker length.
- Trifluoroacetate salt form for improved handling and solubility.
- High purity suitable for chemical synthesis (listed as 99.73%).
- Soluble in DMSO for convenient formulation and reactions.
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Medchemexpress LLC Amine-PEG-amine (MW 5000) | 95.0% | 100 MG
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Amine-PEG-amine (MW 5000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds consisting of two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. The product is intended for research use only.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins
- Intended for research use only
- Solid appearance
- White to off-white color
- Molecular weight of 5000 (average)
- 95.0% purity
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Medchemexpress LLC Amine-PEG3-desthiobiotin | 2237234-71-6 | 99.9% | C18H36N4O5 | 10MG
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Amine-PEG3-Desthiobiotin is a PEG-based bifunctional linker combining a short PEG3 spacer, a terminal primary amine, and a desthiobiotin affinity tag. It is designed for PROTAC assembly, bioconjugation, and affinity-capture workflows where reversible binding to streptavidin/avidin aids purification and enrichment.
- Terminal primary amine for efficient coupling to carboxyl or activated ester functionalities.
- Desthiobiotin tag enables reversible affinity capture with streptavidin/avidin systems.
- PEG3 spacer improves solubility and reduces steric hindrance between binding partners.
- High chemical purity suitable for synthetic and analytical applications.
- Available in multiple small-scale quantities to support method development and optimization.
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Medchemexpress LLC 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido- | 1800414-71-4 | MFCD08274605 | >98.0% | C24H50N4O11 | 100 MG
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Azido-PEG11-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an azide group and an amine group. The product appears as a colorless to light yellow liquid and is intended for research use only, not for medical applications.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an azide group and an amine group
- Colorless to light yellow liquid
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | MFCD03453246 | ≥97.0% | C22H46N4O10 | 5 G
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Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. PROTACs themselves are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Utilized in the synthesis of PROTACs
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eMolecules 58794-09-5 | 7-bromoisoquinoline | AA Blocks LLC | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 2g | 795063184
7-bromoisoquinoline | AA Blocks LLC | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 2g | 795063184
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eMolecules 859924-25-7 | 6-aminoquinoline-4-carboxylic acid | MFCD09837175 | 1g
Pharmablock | 6-aminoquinoline-4-carboxylic acid | 1g | 551240925 | PBKR2085 | 859924-25-7 | MFCD09837175 | 188.186 | C10H8N2O2
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Synthonix - Stock | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 250mg | 525910353
7-Bromoisoquinoline | Synthonix - Stock | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 250mg | 525910353
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eMolecules 4965-36-0 | 7-Bromoquinoline | Chem-Impex | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 5g | 386900399
7-Bromoquinoline | Chem-Impex | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 5g | 386900399
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eMolecules 59107-51-6 | 8-chloronaphthalen-1-amine | Pharmablock | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 5g | 551150668
8-chloronaphthalen-1-amine | Pharmablock | 59107-51-6 | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 5g | 551150668
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